Efficacy and Safety of Gabapentin for Uremic Pruritus and Restless Legs Syndrome in Conservatively Managed Patients With Chronic Kidney Disease
نویسندگان
چکیده
منابع مشابه
Prevalence and correlates of restless legs syndrome in chronic renal failure patients undergoing hemodialysis
Introduction: Restless legs syndrome (RLS) is a sensorimotor disorder characterized by an unpleasant sensation in the legs. This syndrome is a common, yet unrecognized, disorder. The aim of this project was to study the prevalence and correlations of RLS in chronic renal failure patients undergoing hemodialysis in Shahid Rahnemon hospital, Yazd (Iran). Materials and Methods: This descriptive cr...
متن کاملGabapentin enacarbil – clinical efficacy in restless legs syndrome
Restless legs syndrome (RLS) is a sleep-related movement disorder commonly involving an unpleasant urge to move the limbs, typically the legs. Dopaminergic agents represent the first-line therapy for RLS; however, long-term use of such drugs results in worsening symptoms due to "augmentation" or other adverse events. Gabapentin, an analog of the inhibitory neurotransmitter gamma-aminobutyric ac...
متن کاملRestless legs syndrome in patients with chronic obstructive pulmonary disease.
OBJECTIVE To evaluate the prevalence of restless legs syndrome (RLS) in patients with chronic obstructive pulmonary disease (COPD) and the relationship between RLS and clinical/laboratory findings of COPD. METHODS One hundred and thirty-four COPD patients without secondary causes of RLS were included. Thirty-nine (29.1%) patients were diagnosed with RLS and classified as Group 1. The control ...
متن کاملGabapentin Enacarbil: Pharmacotherapy of Restless Legs Syndrome
Restless Legs Syndrome (RLS) is a prevalent sleep-associated movement disorder greatly affecting patients' quality of life (QoL). Several drugs can be used to control this condition although the first-line dopamine agents often cause adverse effects. Non-dopaminergic drugs such as oral gabapentin (GBP) have been more recently advocated. Despite ameliorating RLS symptoms, GBP's pharmacokinetic l...
متن کاملUremic Restless Legs Syndrome Pleads "Not Guilty".
there was no significant association between RLS and 3-year mortality, either with age and gender as covariates [6] . In the current issue of the American Journal of Nephrology , an unprecedented 15-year follow-up of RLS survivorship is presented by Baiardi et al. [7] . These investigators demonstrate that RLS-HD patients had a lower mortality rate compared to those HD patients without the synd...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 2015
ISSN: 0885-3924
DOI: 10.1016/j.jpainsymman.2014.08.010